Probably the Order of the Stick will always be considered a D&D comic.  But it hasn’t been, for quite a while.  By by rough count, the last ten strips contain about five D&D references, total.  It’s basically a fantasy comic that occasionally uses D&D jokes.  (He’s actually using anachronisms and pop culture references more than D&D.)

This isn’t necessarily a bad thing.  On the other hand I’m looking forward to Chainmail Bikini starting up again.